RESEARCH ALERT
Some vapes use added chemicals to create a cold or icy feeling. New research has raised concerns about three of them: WS-23, WS-3 and WS-5. We do not yet know how common they are in Wales.
Information / Nicotine withdrawal
Nicotine withdrawal: symptoms & timeline
When someone regularly uses nicotine, their body and brain adapt to it. Cutting down or stopping can bring temporary withdrawal symptoms – whether the nicotine came from cigarettes, vapes or another nicotine product.
Last reviewed: 25th September 2026
QUICK ANSWER
Withdrawal can start within hours and is usually strongest in the first few days.
NHS guidance says symptoms after stopping smoking are usually strongest in the first week, especially the first three days, and last around 3–4 weeks on average. Experiences vary, and some symptoms can last longer.
Common nicotine withdrawal symptoms
Cravings
Strong urges to use nicotine, often triggered by routines, stress or seeing other people use it.
Irritability & restlessness
Feeling tense, impatient, frustrated or unable to settle.
Concentration
Finding it harder to focus or feeling mentally distracted for a while.
Sleep & mood
Some people notice sleep changes, anxiety, low mood or feeling more emotional.
A rough timeline
First few hours
Cravings and restlessness can begin as nicotine levels fall.
Days 1–3
Symptoms are often at their strongest. This is a common point for cravings, irritability and concentration problems.
First week
Symptoms can still be strong, but many people start noticing periods where cravings are easier to manage.
Around 3–4 weeks
For many people, most withdrawal symptoms have eased substantially. Some habits or triggers can last longer.
Withdrawal is not the same as a trigger
Nicotine withdrawal is the body adjusting to lower nicotine levels. A trigger is a situation, feeling or routine that has become linked with using nicotine – for example a break at work, a car journey, stress or being with friends who vape.
Both can create cravings, which is why a plan usually works better than relying on willpower alone.
What can make withdrawal easier?
If you are stopping smoking
Licensed NRT, stop-smoking medicines, vaping and behavioural support can all reduce the chance that withdrawal pulls you back to cigarettes.
If you are stopping vaping
You can reduce nicotine strength, increase the time between vaping, change routines and make a plan for cravings.
If a young person wants to stop
Keep the conversation supportive and practical. Look at dependence, triggers, access and what support they are comfortable using.
When symptoms do not fit ordinary withdrawal
Nicotine withdrawal can feel uncomfortable, but severe symptoms such as collapse, seizures, severe breathing difficulty or serious confusion are not ordinary withdrawal. Seek urgent medical help if someone is seriously unwell.
Sources & further reading
ASH Wales
Why nicotine dependence develops and why smoking creates the greatest health risk.
LATEST
Latest updates on this topic
2 October 2026
New Welsh report highlights confusion over vaping harms as duty begins
More than half of Welsh adults who have heard of vapes wrongly believe vaping is as harmful as smoking or worse, new ASH Wales…
Read update1 October 2026
New vaping duty comes into force across Wales today
A new UK excise duty on vaping products starts today, 1 October 2026. Here is what the £2.20 per 10ml duty, new vape duty…
Read update25 September 2026
Youth smoking and vaping in Wales: what the latest 2025 data tells us
New 2025 SHRN data shows regular vaping and smoking have fallen among secondary school learners in Wales. We look at the latest figures, what…
Read update

